Deleted unnecessary information and made some corrections at the start of S6
Varshan: Heart of Maglinant 4
Before S5, each part such as the femur was required, but it has been unified to only the heart. Materials such as femur bones can be exchanged for hearts by alchemists
Confirmed or high probability: Whisper Tree reward
Low probability: Random drop from Elite, Local Event, Treasure Goblin, Hellborn, Blood Maiden
Grigoire: Living Steel 12
Confirmed or high probability: Helltide Treasure Box
Low probability: Random drop from Elite, Local Event, Treasure Goblin, Whisper Box, Hellborn, Blood Maiden
Ice Beast: Distilled Terror 12
Before S5, you had to create a crest and enter the dungeon, but this has been changed to a method of directly accessing the dungeon like other end bosses
Confirmed or high probability: Nightmare dungeon clear reward
Low probability: Elite, Local Event, Treasure Goblin, Hellborn, Blood Maiden
Zia: Exquisite Blood 12
Confirmed or high probability: Blood Maiden, Legion, World Boss
Low probability: Elite, Local Event, Treasure Goblin, Hellborn, Blood Maiden
Duriel: Fragment of pain 2/Egg covered in mucus 2
Fragment of pain
= Guaranteed drop when defeating Grigoire
Rarely dropped from world bosses
Eggs covered in mucus
= Guaranteed drop when defeating Virshan
Rarely dropped from world bosses
Andariel: Sandburn Shackles 2, Needleprick Doll 2
Shackles of Sandburn
= Guaranteed drop when defeating Zia
Rarely dropped from world bosses
Needle doll
= Guaranteed drop when defeating the ice beast
Rarely dropped from world bosses
Unique with a chance of being dropped by each end boss
This is a bit old information, so just for reference only.
*Andariel is the same drop as Duriel.
