The vampires in "Stalker 2: Heart of Chernobyl" are very powerful mutant enemies in the game. If you want to fight a vampire for the first time, you can use an AK47 or the gun you picked up in the bunker to shoot from the waist. It was fast and accurate, and at the same time, it kept facing him in a straight line, so that it would sprint back and jump without any time to adjust.
How to fight a vampire when you first meet him in STALKER 2: Heart of Chernobyl
If you want to shoot a vampire, you can use an AK47 or the gun you picked up in the bunker. The waist shot is fast and accurate, keep the front facing him in a straight line, and sprint back before you have time to adjust.
Generally speaking, just hit the shuttle from the front, retreat to the bunker, climb on the table, and have a blast at it.