Williams Manual of Hematology

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A full-color clinical reference covering both common and uncommon blood disorders―distilled from the world’s leading hematology text

Williams Manual of Hematology, Tenth Edition provides a concise, easy-to-navigate compilation of the pathogenic, diagnostic, and therapeutic essentials of blood cell and coagulation protein disorders. Referenced to the classic Williams Hematology, this portable guide has been carefully edited to deliver only the most clinical point-of-care facts, making differential diagnosis faster, easier, and more efficient. This updated edition reflects the latest research and includes more than 100 full-color clinical photographs.

Concise but comprehensive, this complete guide includes sections on:

- Initial Clinical Evaluation

- Disorders of Red Cells

- Disorders of Granulocytes

- Disorders of Monocytes and Macrophages

- Principles of Therapy for Neoplastic Hematological Disorders

- The Clonal Myeloid Disorders

- The Polyclonal Lymphoid Diseases

- The Clonal Lymphoid and Plasma Cell Diseases

- Disorders of Platelet and Hemostasis

- Disorders of Coagulation Proteins

- Thrombosis and Antithrombotic Therapy

- Transfusion and Hemapheresis

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Content licensed from printed edition ISBN 10: 126426920X

Content licensed from printed edition ISBN 13: 978-1264269204

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Author(s): Marshall A. Lichtman, MD ; Kenneth Kaushansky, MD; Josef T. Prchal, MD;, Marshall A. Lichtman, MD ; Kenneth Kaushansky, MD; Josef T. Prchal, MD

Publisher: The McGraw-Hill Companies, Inc.

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Introduction

Williams Manual of Hematology is a comprehensive and authoritative textbook that provides an in-depth understanding of hematology, the study of blood and blood-forming tissues. It covers a wide range of topics, from basic hematology to advanced clinical applications, making it an invaluable resource for medical students, residents, fellows, and practicing physicians.

Section 1: Basic Hematology

This section provides a foundation in the fundamentals of hematology, including:

* Blood cell morphology and function: Discusses the different types of blood cells, their structure, and their role in maintaining homeostasis.

* Hematopoiesis: Covers the process of blood cell production, including the regulation and development of different cell lines.

* Immunology: Explains the role of the immune system in hematology, including antibody production, antigen presentation, and immune deficiencies.

Section 2: Clinical Hematology

This section focuses on the clinical aspects of hematology, covering:

* Anemias: Discusses various types of anemia, their causes, diagnosis, and treatment options.

* Leukemias: Provides an overview of leukemia, including classification, molecular genetics, clinical presentation, and management strategies.

* Lymphomas: Covers the different types of lymphomas, their diagnosis, staging, and treatment approaches.

* Myeloproliferative neoplasms: Describes myeloproliferative disorders, including myelofibrosis, polycythemia vera, and essential thrombocythemia.

Section 3: Hemostasis and Thrombosis

This section explores the complex mechanisms involved in hemostasis and thrombosis, including:

* Platelet function and disorders: Discusses platelet biology, platelet disorders, and their role in bleeding and thrombosis.

* Coagulation and anticoagulants: Covers the coagulation cascade, anticoagulant pathways, and the management of bleeding and thrombotic disorders.

* Fibrinolysis: Explains the process of fibrinolysis, its regulation, and its role in preventing and treating thrombosis.

Section 4: Transfusion Medicine

This section provides a comprehensive overview of transfusion medicine, including:

* Blood components and their uses: Discusses the different blood components, their indications, and their preparation and storage.

* Transfusion reactions: Covers adverse events associated with blood transfusions, including immune reactions and transfusion-related infections.

* Stem cell transplantation: Explains the principles of stem cell transplantation, its indications, and the management of complications.

Section 5: Hematologic Malignancies

This section delves into the molecular biology, diagnosis, and treatment of hematologic malignancies, including:

* Acute leukemias: Covers the different types of acute leukemias, their clinical presentation, and treatment options.

* Chronic leukemias: Discusses the different types of chronic leukemias, their diagnosis, and management strategies.

* Myelodysplastic syndromes: Provides an overview of myelodysplastic syndromes, their classification, and treatment approaches.

* Multiple myeloma: Covers the diagnosis, staging, and treatment of multiple myeloma, including novel therapies.

Conclusion

Williams Manual of Hematology is an essential resource for healthcare professionals involved in the diagnosis, management, and treatment of hematologic disorders. Its comprehensive coverage, up-to-date information, and expert authorship make it an indispensable guide for students, residents, fellows, and practicing physicians seeking to deepen their knowledge and enhance their clinical skills in hematology.